The biggest fallers on the FTSE 100 were Melrose Industries, down 30.7p to 451.9p, Severn Trent, down 154p to 2,499p, Scottish Mortgage Investment Trust, down 45.2p to 768p, United Utilities, down 56p to 1,003p, and CocaCola HBC, down 140p to 2,694p.